When does an overdose occur?

When does an overdose occur?

Caffeine Overdose: It's Rare - But It Happens

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answers (2)

Answer 1
July, 2021

Please specify which specific drug or class of drugs?

If these are legal drugs, then all the symptoms of overdose and poisoning are described in the instructions for the drug.

If you mean drugs, it depends on the species. You can name the general and final clear sign of an overdose - the extinction of body functions. That is, death :)

But I repeat that for a more detailed answer you need a kind of substance.

Answer 2
July, 2021

Good afternoon!

I will answer your question as concretely as possible:

Drug overdose (ethanol can also be included here) occurs, as a rule, in two cases:

  1. When you take a too much dose of the medicine is an absolute overdose
  2. When, when taking a usual dose of a medicine, the rate and nature of the transformations in your body slightly changes the concentration in the blood and tissues relative to standard values ​​- relative overdose

With both types of overdose, there is a significant increase in the main and toxic effects of drugs. For example, in case of an overdose of vasodilators, a sharp drop in pressure occurs, but stimulating drugs - convulsions.

In everyday life, an overdose is especially often manifested by the example of coffee - after 3-4 cups of invigorating coffee, cases are not uncommon when instead of the invigorating effect of this wonderful drink, we close our eyes and appear lethargic.

Why does this happen and how to determine an overdose?

For all medicines so-called pharmacokinetic tests are carried out (in the framework of studies on animals and humans), during which the following processes are determined: absorption, excretion, distribution and metabolism. Based on the results of these studies, the possible doses of drugs for use are deduced:

  • therapeutic dose / Threshold therapeutic dose / average therapeutic dose
  • Single dose / Higher single dose
  • Daily dose / Highest daily dose
  • .....
  • Toxic dose / lethal dose

Toxic doses cause pathological changes in our body that are not fatal, which are subdivided into minimum, average and maximum,

Lethal doses - cause death. They are also subdivided into minimum, medium and absolute

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