I will say right away, it has been tested on myself, firstly, you cannot eat 3-4 times a month, such a property of LSD that it does not pull, and you refuse it yourself, more than enough once a month, well, the ceiling is 2, with at intervals of 2-3 weeks, the only thing can be flashbacks, which, by the way, keep you within the framework of eating very often, psychological dependence can arise, there is not enough color in life. It is best not to eat anything at all, but replace these nasty things with sports, although it does not always bring benefits, there should be a measure everywhere. All the world ✌Everyone is kind 😉
"Practitioners must take into account some of the effects of these substances, namely their ability to influence our consciousness, the very core of ourselves. The history of LSD today sufficiently demonstrates the catastrophic consequences that can occur when the depth of its effects is underestimated and this substance is perceived as a drug that can be taken for pleasure. Misuse and inappropriate use has made LSD my problem child. "
Albert Hofmann. LSD is my problem child
LSD itself is a relatively safe drug (for the powerful effects it does). In Cohen's experiment, on average, 1000 receptions accounted for only 1.8 acute psychosis within two days after ingestion (and this in a medical institution with an experimental doctor - such a setting was unanimously branded with shame by LSD adherents as provoking psychosis).
LSD has extremely low toxicity and is generally well tolerated by the body without causing clinically significant side effects. Does not cause physical dependence.
Psychological addiction, if you try, can be earned (LSD involves the dopaminergic system, which is responsible for the pleasure center), but the ability of LSD to induce it is relatively low. This does not mean "Take LSD calmly, you will get nothing." The ability to induce psychological dependence in LSD is low among other psychoactive substances. And compared to going to school, for example, it is high.
The consequences of long-term LSD use are not well understood.
Systematically (daily, for 90 days) rats taking LSD showed a spectrum of abnormal behavior similar to that observed in rats with a model of schizophrenia: hyperactivity, anhedonia, low social interaction. The experimenters performed RNA sequencing in the medial prefrontal cortex 30 days after the end of the intake. LSD altered gene expression in the medial prefrontal cortex towards a profile associated with schizophrenia. [Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia. David A. Martin, Danuta Marona-Lewicka, David E. Nichols, Charles D. Nichols, 2014]
It makes sense to assume that the systematic intake of LSD changes the sensitivity and / or the number of dopamine receptors and, accordingly, provokes emotional disorders.
I have a description of the unpleasant consequences of taking LSD every two weeks for six months (male, 15 years old):
there are great chances of catching an infection called hppd (long-term disorder of perception of reality), along with depersonalization, derealization, etc. at one time I went through psychedelics and it all began: I did not recognize myself in the mirror, all movements seemed "not my own" and that someone was controlling me and I was just sitting inside, the visuals were like a post-effect from acid, but a little weaker, constantly in the periphery of vision someone rubbed and watched me from behind the wall / door, VERY strange perception of the world and society, people walk and everyone talks like `` yes, I'll be there in 5 minutes, come on tomorrow, I'll go now, well, come on then ...> and all their words stand out and sound very loud, VERY frequent and VERY scary steps, you can get rid of anything because the world is unusual and as a rule it causes alarm. in general, it really interferes with life, sometimes there are seizures (you see a beautiful fractal and you can’t look away, you don’t react to anything, think, suddenly it will happen at school / work). it passes over time (it does not lend itself to almost any treatment), if you continue to lead such a rash lifestyle and use it whenever you get it, then prepare your suitcase in a dork! you can run to such a state that there will be literally endless bad. it may appear even after the first trip, even after the hundredth, depends on the body, but I know for sure that if you read articles on the Internet and use it once a month, then there will be very, very little harm)
Personally, my opinion is that this is too often and simply wrong (more on this later in the answer). First, about the harm. LSD, although it is often presented as a kind of monster, taking which every second person tries to go out the window, according to various studies, carries relatively little harm to human health, and the dependence on it is potentially not so great. While this is not a drug that makes you just happy, unlike ecstasy, for example, its effect is more complex and not always pleasant.
Why do I think this is too often and simply wrong - the LSD trip, in theory, should be something that you can later think about, work out and integrate this experience into my life. Not just entertainment for slightly different purposes. It is like something special, which in ancient times could be mystical rituals that open the door to another universe. They are not held every day, and for good reason.
Among other things, LSD can cause psychological trauma in the event of a bad trip and, as a result, increased anxiety, and it can take a lot of time to recover from this ... And if you have an unstable psyche, or a very unfortunate set and setting, then there are more risks and potential harm when using LSD.
And finally, LSD is really not well understood in terms of long-term effects. Much less than, say, amphetamine, cocaine, or opioids. So if you decide to take it often, then it will be at your own peril and risk. And in general, the human psyche is very complex, so Alexander Shulgin invented and tried the sea in-in, and it seems nothing, but no one can guarantee that everything will be all right with you too.
Psychological dependence is caused by any source of pleasure, although LSD is such a thing that it is far from the fact that you will get pleasure. This is the main and danger, if for physical health it does not carry much harm, then for mental - quite. Yes, you can hear enough stories about the head thrown out the window, but this, in real life, will not happen. Since awareness does not completely disappear for such a situation to occur. But to be driven over by a trifle to such an extent that you will become really scared for your life is easy. And you don't need a serious reason. If you don't have the most stable psyche, if you are often sad for no reason, it is better not to use dissociatives.
There are currently no known long-term physical health effects from LSD use at usual recreational doses. Recent research has shown that there is no increased risk of mental illness for those who use LSD compared to those who do not.
LSD can cause mental addiction, but it is usually a "self-regulating addiction". The fact is that, unlike, for example, stimulants, the effect of a psychedelic is not predictable and not always pleasant. The more often you use it, the more mundane and meaningless each technique will become. In addition, if your quality of life begins to deteriorate due to substance abuse, it will negatively affect its effects, which will contribute to stopping the use, unlike stimulants - the worse your life, the more you want to use the stimulant so that it gets better for a short time and it will get better, no matter how bad it is, because the effect of the stimulant is always the same.
There is a subtlety. Yes, LSD does not destroy your body (I didn’t check it myself, but the wiki says so). But it causes psychological dependence, ie changes the way your brain works so that the absence of harm to the liver, for example, no longer looks like such a plus. Stupid example: if you decide on LSD that your head flew out the window and jump to catch it, then the pathologist doesn't really care will your liver be healthy or not.