Good afternoon, Oleg! If you have a history of mental disorders, of course, any psychoactive substance can provoke a second psychotic attack.
When taking neuroleptics, the ability of the nervous system to respond to external and internal stimuli decreases, motor and mental excitement is weakened, anxiety and fear are suppressed. In patients with psychoses, hallucinations, automatisms, delusional ideas stop or completely disappear.
Marijuana increases the risk of developing extrapyramidal effects - movement disorders provoked by antipsychotics. These include involuntary muscle movements, restlessness, tremors, tonic seizures, and other disorders. Clinical studies indicate that marijuana use increases the incidence of psychotic flare-ups in schizophrenic patients, as it reduces the effectiveness of antipsychotic therapy.
Olanzapine (the active ingredient in Zyprexa) and alcohol have one thing in common: they change work central nervous system - brain and spinal cord. When they are taken at the same time, the most likely to increase the sedative effect. Dangerous symptoms occur:
- weakness, lethargy, decreased muscle tone;
- a strong decrease in blood pressure, dizziness, fainting;
- respiratory depression (superficiality and decrease in respiratory cycles);
- disturbances of consciousness of varying degrees, up to coma;
- instability of the heart rhythm, cardiac arrest.