Is it true that grapefruit juice should not be taken with medicine? And what happens if you drink them alcohol or drugs, the effect will increase?

Is it true that grapefruit juice should not be taken with medicine? And what happens if you drink them alcohol or drugs, the effect will increase?

FDA Warnings: Grapefruit Juice and Some Drugs Don't Mix due to food drug interactions

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answers (2)

Answer 1
May, 2021

Grapefruit inhibits the liver enzyme responsible for the metabolism of certain substances. Therefore, from grapefruit juice, the concentration of certain medications in the blood can remain high for longer than it was intended by the creators of the drug, which can be dangerous. At the same time, prodrugs may not be metabolized into the active substance.

You can read more about this, for example, here: https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions

Answer 2
May, 2021

The thing is that grapefruit activates the activity of liver enzymes. Because of this, the metabolism of drugs changes - they are destroyed faster. But not only grapefruit affects metabolism, but also alcohol, some sleeping pills. Therefore, always refer to the directions in the instructions for the preparations.
Grapefruit juice does not enhance the effect of alcohol and intoxicants.

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