Rest, good nutrition, reducing the load. And then, after all, many will take on a bunch of obligations, and then they are surprised to ask "why did my joints fall apart and my bones broke, how to deal with it?".
As an option - go in for sports) sport perfectly disperses psychological fatigue. A healthy mind in a healthy body and all that.
First, go to a therapist and take a blood test, perhaps the reason for your discomfort lies in the disorders of the body (for example, low hemoglobin). Of the "cheap and angry" tonic drugs, you can advise to drink tincture of Eleutherococcus or ginseng (see instructions for use). These are the most primitive means, but quite effective. You can also try to get enough sleep))