How substantiated are the statements about the genetic degeneration of mankind due to the fact that medicine bears everyone in a row, and then these people pass on defective genes?

How substantiated are the statements about the genetic degeneration of mankind due to the fact that medicine bears everyone in a row, and then these people pass on defective genes?

2018 FAST Science Summit - Gene Therapy for Angelman Syndrome

Previous questionHow do I find a good dentist? Not expensive
Next questionHave you ever had dreams that cause an incomprehensible sense of fear?

answers (3)

Answer 1
January, 2021

We are seven billion, so we are not in danger of degeneration. The larger the population, the richer its gene pool. Plus, now more and more often people of different races and nations meet and make children, which is very good, because it gives more options for variability.

And the fact that people who survive and continue in their descendants, according to the laws evolutions have died, because they bring these descendants not only their "bad" genes, but also their good ones. A diabetic can be a genius, a person with a heart defect can have amazingly beautiful facial features, and a carrier of the hemophilia gene can have a genetically determined tolerance to viral infections. And in the future, these people will pass on ALL their genes. Including those that have not yet found expression in the phenotype. Yes, these are risks for specific parents, but not for humanity. There are already too many of us to degenerate.

Answer 2
January, 2021

Let's just say: there is still some danger in this, but the problem is greatly exaggerated. A person can live up to 12 years as a not very happy disabled person, but humanity as a whole deeply spit on this. There is one important regularity in genetics - the carrier of the dominant allele of the lethal gene dies almost always before the act of reproduction. This is why an apocalyptic plot is impossible, which is why lethal genes are often recessive. If we also take into account the drift of genes, the total number of people on the planet and the easy availability of sexual intercourse with genetically distant relatives, then hysterical cries about the return of eugenics and genetic degeneration sound either like youthful maximalism, or as the asserter's lack of information, or as a delusional idea in a psychiatric sense, since the probability of complete degeneration of the species is approximately equal to the probability that Jupiter will suddenly leave its orbit and be imprinted on our planet.
As for the so-called. of "semi-lethal" and "slightly harmful" alleles, they will be corrected by selection, which still does not stop. And selection by the criterion of viability is monstrously cruel.
As for Markov's article, it just says that the maximum that the accumulation of genetic load can do to a person as a species is to cause inconvenience. In nature, selection often cuts off more than half of immature individuals, even in species with an extremely pronounced concern for the offspring, and I do not understand the panic about 1/10 of abnormally occurring pregnancies.
And the intracellular genetic processes themselves have a huge number of protection mechanisms against errors , up to the repair of damaged areas by DNA polymerase, which is rarely mistaken.
So it is much better to pay attention to the problems in immunology and epidemiology. This is where there really is a lot to think about.

Answer 3
January, 2021

There is some truth in your question, but it's not so bad. Not everyone is able to bear children, but only healthy women (less often, sick, but compensated). In turn, the embryo reaches a term of 40-42 weeks in a living state only if it does not have gross chromosomal rearrangements. Yes, there are rare terrible genetic diseases, but usually people who get them very rarely continue the family for health reasons. More often it happens that healthy people live for themselves and they have a seriously ill child. These are features of the recessive type of inheritance (wikipedia will help). And here the absence of closely related ties is important, as, for example, in some southern and eastern countries. In principle, the genetic burden remains approximately constant, and there is no tendency towards a post-apocalyptic picture. The better fit survives.

Related question

Why is it that uniquely defective genes (all sorts of diseases) are passed on to the offspring, why should it first be born to prove its inadequacy?

Read more

Why are sperm with defects (future people with genetic diseases) ahead of other sperm? Does this mean that the others were even more defective?

Read more

How do you feel about the statement: “We do not decide anything. We are just gene transfer machines, and consciousness is all just a lucky mutation?

Read more

Gene therapy: miracle in our midst

Are there such facts in the history of mankind when a dead person came to life in a coffin? And how has this been proven?

Read more

The pipe smoker's question: Why on candy wrappers, they don't write theses about the dangers of these and there are no inserts with pictures of teeth with caries?

Read more

How is the fact that people with OCD are most often people with a high level of intelligence is explained?

Read more

How do doctors feel about the fact that relatives of patients are not allowed into the intensive care unit?

Read more

removed tooth figure eight, the top row is the penultimate tooth on top, need an implant? 23 years old, I'm afraid that the teeth will become crooked due to the void in the place of the tooth

Read more

Fresh, Natural and Live: Improvement of Diabetes With Diet

Is it true that covid is as dangerous as they say on TV and on the internet, and the bodies of people are burned, crematoria and hospitals are overcrowded, and everyone is finished?

Read more

How to stop thinking about cancer at 18? Do these thoughts replace absolutely everything? Grandfather died of lung cancer, I'm afraid that something will be passed on to me ...?

Read more

How do you feel about the fact that there are a lot of repetitive moments and actions in life? Brushing your teeth, taking out the trash, talking ...?

Read more

A friend is thinking about suicide due to the fact that she is in a difficult relationship with her young man, she is 35 and recently she cut his veins with him in revenge.?

Read more

American films show patients in hospitals with nasal tubes, regardless of the diagnosis. Why is this necessary, and why are these tubes given to everyone?

Read more

Disease and Illness as Narcissistic Dynamics

If everyone knows about the dangers of sulfates, silicones and parabens in cosmetics, why are they still added?

Read more

These are the symptoms of arrhythmia: when the heart stumbles, the rhythm slows down in half for a few seconds and then the rhythm starts running again?

My heart rate is within normal limits: 70-90 beats. in min. Nothing hurts. But sometimes arrhythmia is clearly felt: when the heart stumbles, the rhythm slows down twice for a few seconds (at these moments the heart makes several intensified beats), and then the rhythm starts running again. Coul...

Read more

If genital HPV exists in more than 60% of people, then why not sound the alarm, and why few people know about it?

Read more

Can a person not feel anything despite the fact that he has never felt love on himself? Only hate and anger from people? Is there someone like that?

Read more

Are sex and masturbation different in terms of effects on the body? (a question to the fact that doctors often advise singles to have a partner)

Read more

The Andromeda Strain by Michael Crichton [Full Sci-Fi Audiobook]

Are there any advantages to the fact that most people think in stereotypes and imposed attitudes and do not include critical thinking?

Read more

Is it possible, after becoming a certified specialist in the specialty "Manager ...", to go to graduate school in medicine and then become a candidate of medical sciences?

Read more