How do leukocytes know where the infection is?

How do leukocytes know where the infection is?

How Do White Blood Cells Fight Infection?

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answers (2)

Answer 1
July, 2021

The resource is not highly specialized, therefore, I believe that information is presented in the most simplified form: when inflammation occurs, substances are released that call these leukocytes (the previously mentioned chemokines / chemoattractants). like as you know, in the ocean the blood attracts sharks to itself, something like that can be said in this case.

Answer 2
July, 2021

Stage 0 . Alien cell on its way into the body The first protective barrier - skin and mucous membranes - comes into play. At this stage, the resistance of the immune system of the bacteria is too low.

Stage 1. The alien cell has entered the body.

The second protective barrier is the attack of phagocytes (absorption of bacteria) ... A characteristic sign is a sharp increase in the level of leukocytes in the blood. At this stage of the reaction, phagocytes do not recognize foreign cells by their type.

Stage 2 . The alien cell has passed the II barrier. The actions of the immune system include 3 consecutive reactions.

Attack of macrophages. Recognition of bacteria by macrophages by type —► Decomposition of bacteria —► "Report" of macrophages to T-helpers about the appearance of a foreign cell in the body.

Work of T-lymphocytes. Recognition of bacteria by type —► Determination of the presence of a bacterium of this type, which has ever penetrated into the body —► "Report" of T-lymphocytes to B-lymphocytes on the preparation of the reagent for the final reaction.

B-lymphocytes work. Production of antibodies (immunoglobulins) - ► the destruction of bacteria by antibodies by gluing, precipitating or dissolving.

Stage 3 . Final destruction of the foreign cell. Stopping T-suppressors of the immune response.

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