As for me, the best way is to change the environment, but not to reduce mental activity, just to redirect it in a different direction.
In order not to lose physical shape and get "relaxation", you can go on a hiking trip, there are quite a few options.
Learn something for yourself. For example, as a person who sits on the pope most of the time, I am attracted by wood turning and bar mixology, which I want to master.
The new business will allow me to completely distract myself from your "classic" busyness and allow not lose the grip with which you take on work (i.e. after your vacation you will not suffer from procrastination at the workplace, and accordingly you will do everything on time and with pleasure.)
With an increased stress response (irritability), many are helped, for example, by ginseng, which lowers the level of the stress hormone cortisol.
If the stress was long enough, then cortisol triggered "pro-inflammatory" reactions in the brain. In this case, pessimism and low mood may prevail in the personality structure. In such cases, antidepressants help - for example, SSRIs groups.
In order to recover, you need to get out of the stressful environment, find a zone for yourself that will be as comfortable as possible. No need to break the framework, strive for something new. The work of our body is cyclical and the rise must necessarily be followed by a decline, otherwise it is impossible. So you don't need to strain and just relax. Spend more time with family, good friends, less conflict with people, learn to make compromises. The main thing is not to rest by means of "detachment", i.e. hangouts, with alcohol and drugs, this will further aggravate the situation. You need to understand that if you devote time to work, then you choose it as a priority in your activity and besides it you have rest and self-development (which should always be). Do not look for difficulties, look for comfort , but do not completely relax, this will then reflect badly on your activities.