I myself take sweeteners and sugar substitutes. It must be remembered that in such questions "is this or that food product harmful?" - one rule is important: in what doses and for how long to take?
There is a recent study that fructose provokes many diseases and even cancer. Does this mean that now you need to stop eating apples, oranges, bananas?
About sweeteners. In order not to write for a long time, read the information
Just give the figures for the maximum safe doses of the main sugar substitutes:
aspartame - 50 mg / kg body weight per day;
sucralose - 5 mg / kg body weight per day;
cyclamate - 11 mg / kg body weight per day;
saccharin - 5 mg / kg body weight per day;
acesulfame potassium - 15 mg / kg body weight per day.
The maximum safe dose is understood as the amount of a substance, the use of which every day for many months and years does not reliably harm health.